Better Health and Better World,
through Integration of Molecular Pathology (Including Omics) and Population Health Data Science
Precision Medicine, Precision Prevention, and Precision Public Health
Welcome to the Ogino MPE Lab home page!
(MPE = Molecular Pathological Epidemiology)
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Please also visit
Division of MPE Molecular Pathological Epidemiology (aka, Program in MPE)
in Department of Pathology, Brigham and Women's Hospital
Harvard T.H. Chan School of Public Health
Shuji Ogino, MD, PhD, MS (Principal Investigator)
Chief, Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital
Professor of Pathology at Harvard Medical School, Dana-Farber Cancer Institute, Brigham and Women's Hospital
Professor in the Department of Epidemiology at Harvard T.H. Chan School of Public Health
NCI R35 Outstanding Investigator Award (OIA)-funded investigator
Reiko Nishihara, PhD (Co-Principal Investigator)
Assistant Professor of Pathology at Harvard Medical School, and Brigham and Women's Hospital
(titles in transition) Harvard T.H. Chan School of Public Health
Associate Member, Broad Institute of MIT and Harvard
The Ogino MPE Lab and the Division of MPE Molecular Pathological Epidemiology (Brigham and Women's Hospital) host the International Molecular Pathological Epidemiology (MPE) Meeting Series
Introduction and goals:
The International Molecular Pathological Epidemiology (MPE) Meeting Series has been open to research community around the world, with free registration. The First, Second, and Third International MPE Meetings were successfully held in Boston, MA, USA, in April 2013, December 2014, and May 2016, respectively.
This is the only meeting series to focus on MPE as a single unified field.
As an important premise of epidemiology, individuals with the same disease generally have similar causes, and exhibit a similar disease evolution. In the past few decades, our knowledge on disease pathogenesis has improved considerably, and disease classification has also transformed, incorporating molecular mechanisms of disease. As a result, Pathology and Epidemiology have now been integrated into the single unified field of Molecular Pathological Epidemiology (MPE). This has opened enormous opportunities.
To advance integrative molecular and population-level health science and address the unique research challenges specific to the field of MPE requires bringing together experts in various fields including pathology, epidemiology, biostatistics, computational biology, bioinformatics, genomics, immunology, and nutritional and environmental sciences. This effort of integrating seemingly divergent fields can lead to a greater understanding of pathogenic processes, and the impact of environmental, dietary, lifestyle, and genetic factors and their interactions. Brainstorming and discussion fostered by the MPE Meeting will lead to the development of new methodologies to address the unique research questions and challenges in this emerging field. Our goals are to:
1. Develop methods to integrate pathology and epidemiology
2. Link pathogenic insights to population impact
3. Educate next generation scientists
This unique meeting can provide an unprecedented opportunity for interdisciplinary collaboration and integration of multiple diverse fields. Eventually, we aim to establish the MPE Meeting as a regular annual science forum, where we can advance population science, and optimize our training and education systems for 21st century medicine and public health.